The Changing Epidemiology of Streptococcus pneumoniae Serotype 19A Clonal Complexes
نویسندگان
چکیده
منابع مشابه
The changing epidemiology of Streptococcus pneumoniae serotype 19A clonal complexes.
Streptococcus pneumoniae is a leading cause of pneumonia throughout the world and a major cause of serious invasive disease, especially in the very young and the elderly. The major virulence factor of S. pneumoniae is its polysaccharide capsule, which can be expressed as 91 different capsular serotypes [1, 2].Seven serotypes (those of high prevalence in children prior to 2000; serotype [sero]4,...
متن کاملPurification of capsular polysaccharide produced by Streptococcus pneumoniae serotype 19A.
Streptococcus pneumoniae is a major cause of invasive infection in young infants and older adults. There are currently 90 capsular serotypes identified and 23 serotypes (1, 2, 3, 4, 5, 6B, 7F, 8, 9N, 9V, 10A, 11A, 12F, 14, 15B, 17F, 18C, 19F, 19A, 20, 22F, 23F, and 33F) are responsible for about 90% of invasive disease. Among the more than 90 different S. pneumoniae serotypes, serotype 19A is g...
متن کاملMolecular epidemiology of serotype 19A Streptococcus pneumoniae among invasive isolates from Alaska, 1986–2010
BACKGROUND After the introduction of the 7-valent pneumococcal conjugate vaccine (PCV7) in Alaska, the incidence of invasive pneumococcal disease (IPD) due to non-vaccine serotypes, particularly serotype 19A, increased. The aim of this study was to describe the molecular epidemiology of IPD due to serotype 19A in Alaska. METHODS IPD data were collected from 1986 to 2010 through population-bas...
متن کاملStreptococcus pneumoniae Serotype 19A in Children, South Korea
Despite the concern of replacement disease, notably by serotype 19A after 7-valent conjugate vaccine (PCV7) use, serotype 19A was increasingly recognized in Korean children before the introduction of PCV7. To understand the dynamics of serogroup 19 prevalence from 1991-2006, we serotyped 538 pediatric pneumococcal isolates. Serogroup 19 isolates (n = 126) were characterized by antimicrobial dru...
متن کاملPostvaccine genetic structure of Streptococcus pneumoniae serotype 19A from children in the United States.
BACKGROUND The introduction of the 7-valent conjugate pneumococcal vaccine (PCV7) in children may result in serotype replacement. We estimated the rate of increase of invasive pneumococcal disease (IPD) caused by serotype 19A in children <5 years old and determined the genetic composition of these isolates. METHODS Cases of IPD between July 1999 and June 2004 were identified through the Activ...
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ژورنال
عنوان ژورنال: Journal of Infectious Diseases
سال: 2011
ISSN: 0022-1899,1537-6613
DOI: 10.1093/infdis/jir056